Table 1

Obesity and AF: Cohort Studies

First Author (Ref. #), YearCohort SourceDates of EnrollmentCountrySubjects (% Women)Mean Age (yrs)Body Mass Index (kg/m2)Body Mass Index Data ReportedFollow-Up (yrs)Cases of AF (%)AF DiagnosisOther Covariates in Model
Wang et al. (26), 2004Framingham Heart and Offspring Studies1979–1983United States5,282 (55%)572,991 (57%) overweight or obeseContinuous and categoricalMean 13.7526 (10.0%)ECGAge, systolic blood pressure, antihypertensive therapy, diabetes, left ventricular hypertrophy, myocardial infarction, congestive heart failure, smoking, cardiac murmur, left atrial size
Frost et al. (27), 2005Danish Diet, Cancer and Health Study1993–1997Denmark47,589 (53%)5626,403 (55%) overweight or obeseContinuous and categoricalMean 5.7553 (1.2%)National health care registryAge, systolic blood pressure, antihypertensive therapy, serum cholesterol, alcohol consumption, smoking, education, diabetes, ischemic heart disease, heart failure, valve disease
Murphy et al. (28), 2006Renfrew-Paisley Study1972–1976Scotland15,402 (54%)548,503 (56%) overweight or obeseContinuous and categoricalMean 20.0175 (1.1%)National hospitalization and death registriesAge, sex, systolic blood pressure, diabetes, cholesterol, forced expiratory volume, smoking, social class
Gami et al. (29), 2007Mayo Clinic1987–2003United States3,542 (34%)49Mean 33ContinuousMean 4.7133 (3.8%)ECGAge, sex, smoking, hypertension, diabetes, ischemic heart disease, heart failure
Rosengren et al. (14), 2009Swedish Primary Prevention Study1970–1973Sweden6,903 (0%)52Mean 22.4Continuous and categoricalMaximum 34.31,253 (18.2%)National hospitalization registryAge, systolic blood pressure, antihypertensive therapy, diabetes, smoking, alcohol, social class
Tedrow et al. (13), 2010Women’s Health Study1993–2004United States34,309 (100%)5516,765 (49%) overweight or obeseContinuous and categoricalMean 12.9834 (2.4%)ECG or medical recordAge, ethnicity, hypertension, hypercholesterolemia, diabetes, alcohol consumption, smoking, physical activity, inflammatory markers
Smith et al. (30), 2009Malmo Diet and Cancer Study1991–1996Sweden30,447 (60%)58Mean 25.8Continuous and categoricalMean 11.21,430 (4.7%)National hospitalization and death registriesAge, sex, myocardial infarction, heart failure, hypertension, diabetes, smoking
Schnabel et al. (31), 2010Age, Gene/Environment Susceptibility-Reykjavik Study2002–2006Iceland4,238 (63%)76Mean 27.0ContinuousMean 5.0226 (5.3%)ECG or hospitalization registriesAge, sex, antihypertensive therapy, PR interval, heart failure
Schnabel et al. (31), 2010Cardiovascular Health Study1989–1990United States9,806 (60%)75Mean 26.4 (Whites), 28.5 (African Americans)ContinuousMean 5.0958 (9.8%)ECG or hospitalization registriesAge, sex, antihypertensive therapy, PR interval, heart failure

AF = atrial fibrillation; ECG = electrocardiogram.