Author + information
- Received March 11, 2017
- Revision received June 27, 2017
- Accepted July 13, 2017
- Published online January 15, 2018.
- Patrizio Pascale, MD∗ (, )
- Laurent Roten, MD,
- Ashok J. Shah, MD,
- Daniel Scherr, MD,
- Yuki Komatsu, MD,
- Khaled Ramoul, MD,
- Matthew Daly, MD,
- Arnaud Denis, MD,
- Nicolas Derval, MD,
- Frédéric Sacher, MD,
- Mélèze Hocini, MD,
- Michel Haïssaguerre, MD and
- Pierre Jaïs, MD
- Hôpital Cardiologique du Haut-Lévêque and Université de Bordeaux, IHU LIRYC ANR-10-IAHU-04, Bordeaux-Pessac, France
- ↵∗Address for correspondence:
Dr. Patrizio Pascale, Service de Cardiologie, Centre Hospitalier Universitaire Vaudois–BH 09-792, Rue du Bugnon 46, 1011 Lausanne, Switzerland.
Objectives The purpose of this study was to describe and identify useful electrocardiographic characteristics to help identify the mechanism of atrial tachycardia (AT) occurring after persistent atrial fibrillation (PsAF) ablation.
Background Electrocardiographic analysis to help identify the mechanism of AT after PsAF ablation is much limited by the fact that remodeling and ablation alter the normal activation pattern.
Methods All consecutive patients who underwent mapping and ablation of AT after PsAF ablation were included. Surface P waves were analyzed during higher (>2:1) grades of atrioventricular block.
Results One hundred ninety-six ATs with visible P waves were identified in 127 patients (macro–re-entry in 57%, centrifugal AT in 43%). One-third displayed low-voltage P waves (≤0.1 mV). An isoelectric line >80 ms was more common in centrifugal compared with macro–re-entrant AT (47% vs. 24%; p < 0.001), but its positive predictive value was limited (60%). A minority of peritricuspid ATs displayed the classic saw-tooth pattern (27% [n = 22]). However, the “precordial transition” (a gradual transition from an upright component in lead V1 to a negative component with progression across the precordium) remained often observed and specifically identified peritricuspid AT (specificity, 98%; sensitivity, 59%). Only 2 unique features could help identify perimitral AT (n = 60). First, the presence of a negative or negative-positive P-wave in any of leads V2 to V6 identified perimitral AT with 97% specificity and 30% sensitivity. Second, a “notched” negative component at the beginning of a positive P-wave in the inferior leads specifically identified clockwise perimitral AT (specificity, 98%; sensitivity, 25%).
Conclusions Only few unique electrocardiographic characteristics help identify the mechanism of AT after PsAF ablation. Knowledge of these characteristics may aid in planning and performing ablation.
Dr. Pascale has received financial support from the Swiss National Science Foundation and the SICPA Foundation. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
All authors attest they are in compliance with human studies committees and animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines, including patient consent where appropriate. For more information, visit the JACC: Clinical Electrophysiology author instructions page.
- Received March 11, 2017.
- Revision received June 27, 2017.
- Accepted July 13, 2017.
- 2018 American College of Cardiology Foundation
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