Author + information
- 1Midyat State Hospital, Cardiology, Mardin, Turkey
- 2Diyarbakir Gazi Yasargil Training and Research Hospital, Department of Cardiology, Turkey
- 3Bingol State Hospital, Cardiology, Bingol, Turkey
- 4Department of Cardiology, Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, Turkey
- 5Department of Cardiology, Division of Electrophysiology, Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, Turkey
- 6Department of Cardiovascular Surgery, Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, Turkey
The number of patients with heart transplantation has dramatically increased in the last decade. There is, however, no sufficient data regarding arrhythmic risk in such patients. To discuss this issue, in the current study we analyzed dispersion of myocardial repolarization using Tp-e interval and Tp-e/QTc ratio in patients with heart transplantation.
This observational study included 38 patients (12 female and 26 male) with heart transplantation with a mean age of 40.2 ± 15.1 years. Noninvasive arrhythmia indicators including Tp-e interval, QTc interval and Tp-e/QTc ratio of these patients were compared with the parameters of 38 well-matched controls.
Noninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, p<0.001), Tp-e/QTc ratio (0.19 ± 0.04 vs 0.16 ± 0.02, p<0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared to normal hearts (Figure).
Patients with heart transplantation have increased myocardial dispersion of repolarization and higher arrhythmia indicators.