Author + information
- D. Pospsil,
- M. Sepsi and
- M. Felsöci
We performed measurements of interventricular conduction times in 62 consecutive patients who signed consent forms and underwent CRT device implant. We acquired very interesting data for both ischemic and dilated cardiomyopathy HF etiology patients with the use of in-vivo measurements on newly introduced right and left ventricular pacing leads.
We used Biotronik Renamic PSA module for performing rate and voltage dependent pacing protocol (from threshold up to 10 V, from intrinsic rate up to 140 BPM). Every available pacing vector between leads was tested to determine its conduction time in both directions, that means pacing in the right ventricle, signal acquisition in the left ventricle, then vice-versa.
We found major directional dependency of conduction time – anisotropy phenomenon in 2 of 24 (8,3%) patients with ischemic HF etiology and rapidly more – 17 of 38 (44,7%) in patients with dilated cardiomyopathy.
Dilated cardiomyopathy patients have significantly frequent occurrence of interventricular anisotropy which should be taken into consideration while setting of CRT device. Obtained data are being used for CRT optimization and further research at our department.