Author + information
- Received January 13, 2017
- Revision received March 9, 2017
- Accepted April 9, 2017
- Published online October 16, 2017.
- Haisam Ismail, MD,
- Elizabeth Raynor, MD and
- Peter Zimetbaum, MD∗ ()
- ↵∗Address for correspondence:
Dr. Peter Zimetbaum, Department of Cardiology, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, Boston, Massachusetts 02215.
Cardiac involvement is common and may be the presenting or predominant manifestation in a variety of neuromuscular disorders, most notably the inherited muscle disorders, or muscular dystrophies. Cardiac manifestations of the neuromuscular disorders result from pathological involvement of the myocardium and the cardiac conduction system, with resulting cardiomyopathy or rhythm disturbances including supraventricular arrhythmias, life-threatening ventricular arrhythmias, and sudden cardiac death. Many of these neuromuscular disorders are rare and may be unrecognized by even experienced specialists in internal and cardiovascular medicine. Furthermore, the initial cardiac manifestations in these patients are often asymptomatic. The goal of this investigation is to review the scope of cardiac conduction defects and rhythm disturbances in these disorders and to propose some practical recommendations for arrhythmia monitoring and management of these patients.
- atrial fibrillation
- heart block
- muscular dystrophy
- myotonic dystrophy
- sudden cardiac death
The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
All authors attest they are in compliance with human studies committees and animal welfare regulations of the authors’ institutions and Food and Drug Administration guidelines, including patient consent where appropriate. For more information, visit the JACC: Clinical Electrophysiology author instructions page.
- Received January 13, 2017.
- Revision received March 9, 2017.
- Accepted April 9, 2017.