|Inflammatory Cytokine||HR∗||95% CI||p Value|
|TNF-α SR I||1.54||1.16–2.05||0.003|
|TNF-α SR II||1.43||1.09–1.87||0.009|
CI = confidence interval; CRP = C-reactive protein; IL = interleukin; PAI = plasminogen activator inhibitor; SR = soluble receptor; TNF = tumor necrosis factor.
↵∗ Associations between the indicated cytokine and atrial fibrillation were adjusted for race, age, sex, body mass index, tobacco use, alcohol consumption, statin treatment, hypertension, diabetes, coronary artery disease, heart failure, and study site. Inflammatory cytokine concentrations have been log-transformed; the hazard ratio (HR) is interpreted as the increased hazard of incident atrial fibrillation for each doubling of cytokine concentration.